Friday, 9 November 2018

New paper: Language phenotypes in children with sex chromosome trisomies

I'm excited that a new paper from my time working as a Research Assistant with Professor Dorothy Bishop is out, in unrefereed form. It has been published in Wellcome Open Research which is a new open access online journal, where each paper is published before review. The peer review process is open and changes may be made to the paper following review.

The paper describes the language phenotypes of children with sex chromosome trisomies. The other research assistants working on this project and I (there are a quite a few of us!) spent a lot of time driving round the country to see give children with an extra sex chromosome (i.e. XXX, XXY, or XYY) a large battery of tests. We also saw many twins (with no trisomy) who provide control data for this sample.

The paper found that there is large variation in phenotypes across the different trisomies, and concluded that although there is increased risk of language problems in those with a trisomy, there is a range of possible outcomes.

You can read the full paper here.

Reference: Bishop DVM, Brookman-Byrne A, Gratton N et al. Language phenotypes in children with sex chromosome trisomies [version 1; referees: awaiting peer review]. Wellcome Open Res 2018, 3:143 (https://doi.org/10.12688/wellcomeopenres.14904.1).

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